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Dr. Natalia Trayanova gives keynote lecture at IEEE Engineering in Medicine and Biology Society

Date: July 6, 2013

Natalia A. Trayanova, Murray B. Sachs Professor of Biomedical Engineering and the Institute for Computational Medicine, presented a keynote lecture at the 35th Annual Conference of the IEEE Engineering in Medicine and Biology Society. The conference was held on July 3-7 in Osaka, Japan. Natalia's presentation entitled “Modeling Heart Function and Dysfunction” was scheduled for theme 5 in the keynote speaker series.

Click here to view more information about the conference.

To view a pdf abstract of Dr. Trayanova's presentation, click here.


Dr Raimond Winslow gives keynote lecture at 2013 International Conference on Computational Sciences

Date: June 20, 2013

Dr. Raimond Winslow, Raj and Neera Singh Professor, Department of Biomedical Engineering and Director of the Institute for Computational Medicine was among the keynote speakers at the 2013 International Conference on Computational Science held June 5-7, 2013 in Barcelona, Spain. His presentation, entitled "The Emerging Discipline of Computational Medicine," detailed developments by the Institute in the creation of computational models "to capture all that we know about disease and to develop improved therapies tailored to the needs of individuals."

From the ICCS website: "The International Conference on Computational Science is an annual conference that brings together researchers and scientists from mathematics and computer science as basic computing disciplines, researchers from various application areas who are pioneering computational methods in sciences such as physics, chemistry, life sciences, and engineering, as well as in arts and humanitarian fields, to discuss problems and solutions in the area, to identify new issues, and to shape future directions for research."

For more information, visit the 2013 ICCS website or click here to view the presentation slides.


Dr. Natalia Trayanova's Research Featured in Hopkins Medicine News

Date: June 16, 2013

Dr. Natalia Trayanova of the Institute for Computational Medicine was recently featured in the Johns Hopkins Medicine ‘Dome’ Newsletter for her contributions to cardiology research. The article, entitled “Mapping the Heart”, discusses her work towards creating “a model of the heart that would work like Google Maps” through the study of its electrical and mechanical functions.

“Our goal is to learn as much as possible through these noninvasive tests that we are developing,” Trayanova says. “The more we know about heart function at both the theoretical level and the patient-specific level, the more we can improve the current therapies for patients suffering from heart disease.”

Click Here to read the entire article at hopkinsmedicine.org


Dr. Rachel Karchin invited to speak at Carnegie Mellon APGA 2013 Meeting May 3-5

Date: May 1, 2013

Dr. Rachel Karchin, Associate Professor in the Department of Biomedical Engineering and Institute for Computational Medicine, is scheduled to speak at APGA 2013. The meeting entitled "Automated Personal Genome Analysis for Clinical Advisors: Challenges and Solutions" will be held at the Hillman Center for Future-Generation Technologies in the School of Computer Science Complex at Carnegie Mellon University in Pittsburg, PA.

The future of personalized medicine is often envisaged as doctors interrogating a “Dr. in a Box” that integrates multiple streams of data – whole patient genomes, blood tests, scans, and other information – to detect anomalies, diagnose disease, monitor response to therapy, and track changes in health over time. Of particular importance will be the ability to predict disease risk and treatment responsiveness from personal genome information. Developing machine learning software to model the relationships between complex diseases and genome variation is a major challenge.

To read more about the meeting click here to visit the Carnegie Mellon webpage.


Center for Imaging Science Hosting Symposium to Celebrate its 15 Years of Science

Date: April 25, 2013

The Center for Imaging Science will be hosting a Symposium on May 17 & 18 to celebrate its 15 years of science. The event will begin Friday May 17th at 1:00 PM at the Sheraton Baltimore North, and will continue Saturday 9:00 AM on the Johns Hopkins University Homewood campus at the Hodson Hall Boardroom.

The Center's two days of celebrations will feature talks from leading scientists in Medical Imaging, Computational Vision and Computational Biology, three areas upon which the Center for Imaging Science has focused over its existence. Our renowned speakers include Nicholas Ayache from INRIA, Stuart Geman from Brown University, Richard Hartley from National ICT Australia, Alfred Hero from the University of Michigan, Alain Trouvé from Ecole Normale Supérieure, Cachan and Raimond Winslow of the Johns Hopkins University.

To view a pdf brochure for the symposium event with an itinerary and full list of speakers, click here.


BME Transition Generator receives $150,000 from JHU PII

Date: April 2, 2013

A proposal put forth by two BME students, Iraj Hosseini, a 4th year PhD Candidate in the Institute for Computational Medicine lab of Dr. Feilim Mac Gabhann, and Shiva Razavi, co-president of the BME PhD Council, was awarded $150,000 from the Office of the Provost, as part of its PhD Innovation Initiative (PII) to support bold, creative, culture‐changing ideas for transforming PhD education at Johns Hopkins. The winning proposal, titled "BME Transition Generator" was the result of multi-faceted teamwork between BME PhD students, the faculty and the staff. Iraj Hosseini and Shiva Razavi led the efforts that shaped this proposal. Dr. Elliot McVeigh and Dr. Youseph Yazdi served on the advisory panel, while Hong Lan, Chuck Montague and Catherine Schoonover from the BME staff played an instrumental role. The valuable feedback received from surveying the BME PhD student body was a critical basis for their success.

From the proposal abstract:

“Traditionally, the mission of the doctoral programs has been to train future university faculty; however, there is increasing enthusiasm among PhD students to pursue careers in industry, entrepreneurship and consulting. As of 2012, about 26% of biomedical PhDs have tenured or tenure-track faculty positions, compared to 34% in 1993. It is therefore essential for our educational institutions to accept this shift in the academic market and offer our students additional mentorship and training that will make them competitive.

The gap between current training objectives and career outcomes brings into stark relief the need for a proactive role that universities need to pursue in preparing PhD students for both academic and alternative career paths. The JHU Department of Biomedical Engineering proposes to achieve this additional training by establishing a new departmental center, the BME Transition Generator. This center will serve two primary functions: (i) facilitating internships for the current PhD students; (ii) providing additional training opportunities to address the need for developing professional skills.”

Congratulations to the BME PII team on their outstanding achievement!


Dr. Michael Miller to receive McDonald Mentoring Award

Date: March 29, 2013

Dr. Michael Miller will receive the Capers and Marion McDonald Award for Excellence in Mentoring and Advising from the Whiting School of Engineering at May 6th Convocation. Often referred to simply as the "McDonald Mentoring Award," this program recognizes and honors diverse professionals in engineering and the applied sciences who, as exemplary mentors and advisors, have significantly and consistently supported the personal and professional development of others. In a university setting, these efforts will have included students and colleagues. In industry, government, or service organizations, they may have included a variety of developing personnel.

Beginning with the first award in April 2005, the program is designed to celebrate annually those who have enduringly engaged minds, elevated spirits, and stimulated best efforts. It also aspires to help spread the virtues of excellent mentoring and advising in the engineering and applied sciences community.

The program is endowed by Capers W. McDonald and Marion K. McDonald to operate through six supporting institutions. An international recognition is part of the annual society-level award programs of ASME. U. S. national honorees are recognized through the engineering honor society, Tau Beta Pi. Other outstanding mentors are selected annually through similarly-endowed institutional programs at Duke University, Harvard University, Johns Hopkins University, and Massachusetts Institute of Technology – universities where sponsor Capers McDonald has been privileged to have been a learner, either as a student or faculty member.


Dr. Natalia Trayanova’s recent application to NHLBI recommended for funding with percentile of 1%

Date: March 21, 2013

Dr. Natalia Trayanova’s recent application to the National Heart, Lung and Blood Institute, “Predicting the Optimal Ablation Targets for Infarct-related Ventricular Tachycardia” has been recommended for funding with the remarkable percentile of 1%. This caps a string of achievements in the past year for Dr. Trayanova, the Murray B. Sachs Professor of Biomedical Engineering and the Institute for Computational Medicine, who in February gave the Keynote Address for the Society for Industrial and Applied Mathematics Conference on Computational Science and Engineering, in Boston.

Congratulations Natalia!


Dr. Rachel Karchin promoted to Associate Professor with tenure

Date: March 11, 2013


Dr. Rachel Karchin

The Institute for Computational Medicine is pleased to announce that Dr. Rachel Karchin has been promoted to Associate Professor with tenure effective July 1, 2013. Dr. Karchin holds appointments with the Institute for Computational Medicine, the Department of Biomedical Engineering, and the Department of Computer Science in the Johns Hopkins Whiting School of Engineering, as well as with the Institute of Genetic Medicine in the Johns Hopkins School of Medicine. The focus of her research is the development of computational methods to assess the impact of DNA sequence variation on human health. In 2009, she received a National Science Foundation CAREER Award to support research in modeling missense mutation. In April of 2013 she will receive a National Science Foundation Advances in Biological Informatics Innovation Grant. This 3-year, $695K award will fund her research collaboration with Dr. Manel Camps of the University of California, Santa Cruz, to develop a new method to model higher order mutation interactions by combining evolutionary genetics, network models, and protein sequence analysis. Dr. Karchin has also received funding from the National Cancer Institute, the National Institute of Mental Health, the Susan G. Komen Foundation, and the Cystic Fibrosis Foundation, and she enjoys many productive collaborations with research faculty in the School of Medicine’s Department of Oncology and elsewhere within Johns Hopkins.

Dr. Raimond Winslow, Director of the Institute for Computational Medicine states "Dr. Karchin is blazing a new frontier of cancer biology in which computational modeling will be used to identify the gene mutations which drive tumor progression. Ultimately, this computational approach will lead to more personalized, precision cancer therapies. Her work is receiving international recognition, and we are all proud that she is a part of the Institute for Computational Medicine".

For more information on Dr. Karchin’s work, click here to view her profile.

Please join us in congratulating Rachel on this tremendous achievement!


Kathleen McDowell awarded for poster at Gordon Research Conference on Cardiac Arrhythmia Mechanisms

Date: February 28, 2013

Kathleen McDowell, a 5th year PhD Candidate in the lab of Dr. Natalia Trayanova, received 1st place in the Student/Trainee Poster Competition at the Gordon Research Conference on Cardiac Arrhythmia Mechanisms. She presented her research entitled, "Investigating the Arrhythmogenic Effects of Atrial Fibrosis in Patient-Specific Models". The 2013 Gordon Research Conference (GRC) on Cardiac Arrhythmia Mechanisms was held on February 17-22 and focused on integrating basic and translational science with clinically relevant topics. Click here to view more information on the conference.

Congratulations Kathleen!



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