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Research from Dr. Trayanova's lab published in Nature Communications and featured on JHU News site

Date: August 28, 2013

Dr. Natalia Trayanova, Murray B. Sachs Professor of Biomedical Engineering and member of the Institute for Computational Medicine was featured in a recent news release on the Johns Hopkins University News website. The article, entitled “Researchers Aim to Use Light—Not Electric Jolts—to Restore Healthy Heartbeats” was released on August 28 along with publication of the research in Nature Communications.

“In a paper published today in the online journal Nature Communications, five biomedical engineers from Johns Hopkins and Stony Brook universities described their plan to use biological lab data and an intricate computer model to devise a better way to heal ailing hearts. Other scientists are already using light-sensitive cells to control certain activities in the brain. The Johns Hopkins-Stony Brook researchers say they plan to give this technique a cardiac twist so that doctors in the near future will be able to use low-energy light to solve serious heart problems such as arrhythmia.”

To read the full story, click here.

** Update: November 19 ** The story was featured in the Baltimore Sun here: Light could replace shock to regulate hearts

U.S. and international coverage:

Slate Magazine, Aug. 30: Future Heart Attack Treatments Will Use Light, Not Volts, to Keep Your Heart Beating
CNET News (CBS Interactive), Aug. 28: Scientists shine a light on irregular heart beats
BioOptics World, Aug. 30: Optogenetics could work to correct life-threatening arrhythmias
Diagnostic and Interventional Cardiology, Sept. 6: Researchers Aim to Use Light — Not Electric Jolts — to Restore Healthy Heartbeats
Motherboard, Aug. 30: The Pacemakers of the Future Will Keep Your Heart Beating With Light
GMA News (The Philippines), Aug. 30: US researchers eye light beams to treat irregular heartbeats
Ivanhoe’s Medical Breakthroughs, Sep. 3: Using Light Instead of Electric Jolts to Restore Heartbeats
Medgadget, Aug. 28: Virtual Heart Beats to the Rhythm of the Light
Zimbabwe Star, Aug. 31: Light-based technology rather than electric jolts may in future restore healthy heartbeats (Bolivia), Sept. 2: Usarán luz para estimular el corazón que late con arritmia (France), Sept. 2: Infarctus : de la lumière pour ranimer le cœur (Poland), Sept. 1: Światło zamiast impulsów elektrycznych w defibrylatorach przyszłości (France), Sept. 1: Coeur : utiliser de la lumière en guise de défibrillateur
Scientific Computing, Sept. 3: Using Light — Not Electric Jolts — to Restore Healthy Heartbeats (Hungary), Sept. 3: Újraélesztés: már fénnyel is lehetséges?
Big News Network (Australia), Aug. 29: Light could replace electric jolts to restore healthy heartbeats
Hot Digital News, Aug. 28: Scientists shine a light on irregular heart beats, Aug. 29: Potentially Replacing Electricity with Light for Pacemakers and Defibrillators, Aug. 29: A New Kind of Defibrillator On the Horizon
Headlines & Global News, Aug. 28: Researchers Working on Technology to Replace ‘Electric Current’ with ‘Light’ to Restore Heartbeat
ANI News Service (India), Aug. 29: Light could replace electric jolts to restore healthy heartbeats
Toronto Telegraph, Aug. 29: Light could replace electric jolts to restore healthy heartbeats
R&D Magazine, Aug. 28: Researchers aim to use light to restore healthy heartbeats
Science Daily, Aug. 28: Researchers Aim to Use Light -- Not Electric Jolts -- To Restore Healthy Heartbeats
Zee News (India), Aug. 29: Light could replace electric jolts to restore healthy heartbeats
(Other India-based news sites that picked up this ANI article included Yahoo! News – India,,,,,,

More coverage

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Dr. Natalia Trayanova's Research Featured in Johns Hopkins Children's Center News

Date: August 22, 2013

Dr. Natalia Trayanova, Murray B. Sachs Professor of Biomedical Engineering and member of the Institute for Computational Medicine was featured in a recent news release on the Johns Hopkins Children's Center website. The article, entitled “‘Virtual Heart’ Precision-Guides Defibrillator Placement in Children with Heart Disease” describes the Trayanova lab's groundbreaking research in pediatric cardiology. The lab seeks to remove the guesswork from the process of placing defibrillators on children born with heart defects through the use of 3-D virtual heart models.

The full story can be read on the website.

This story has also been featured in: Johns Hopkins Medicine News | JHU Biomedical Engineering News

Hermenegild Arevalo as finalist for Young Investigator Competition at ICE 2013

Date: August 19, 2013

Hermenegild Arevalo, a PhD student in the lab of Dr. Natalia Trayanova, was chosen as one of the finalists in the Young Investigator Competition at the 2013 International Congress on Electrocardiology held in Glasgow, Scotland from August 7-10. This honor is an amazing achievement for Hermenegild, who was competing against applicants from all over the world.

At the conference, Hermenegild presented his recent study, "Patient-Specific MRI-Based Models of Infarcted Hearts Can Predict Risk of Sudden Cardiac Death". For more information on the meeting, visit the ICE 2013 website here.

Congratulations Hermenegild!

University launches The Johns Hopkins Individualized Health Initiative (Hopkins inHealth)

Date: August 6, 2013

The Johns Hopkins Individualized Health Initiative (Hopkins inHealth) aims to develop and implement novel methods and tools to intelligently use information to individualize wellness, early disease detection, and more effective and affordable treatment. It is a University-wide, collaborative venture that is both visionary and pragmatic. The initiative builds on dramatic advances over recent years in biological research, in new technologies that afford an increasingly detailed view of disease, and in computational and data sciences. ICM is delighted that three members of our core faculty have been recruited to participate in the initiative and help advance its goals. Dr. Raimond Winslow, Raj and Neera Singh Professor, Department of Biomedical Engineering and Director for the Institute for Computational Medicine is a member of the Hopkins inHealth Steering Committee, which will meet monthly to guide progress made by the Hopkins inHealth team, investigators, pilot projects, and cores. ICM faculty members Dr. Rachel Karchin, Associate Professor of the Department of Biomedical Engineering, and Dr. Suchi Saria, Assistant Professor in the Computer Science Department in the Whiting School of Engineering and in Health Policy and Management in the Bloomberg School of Public Health, have also been called upon by the inHealth initiative for their respective expertise in the field of “individualized medicine”.

To learn more about Hopkins inHealth, click here, or go directly to information about contributions to the initiative by Dr. Karchin and Dr. Saria.

Sabato Santaniello receives 2 year $150k award from National Science Foundation

Date: July 25, 2013

Sabato Santaniello, a scientist in the lab of Dr. Sridevi Sarma, Assistant Professor at the Institute for Computational Medicine, recently received an award of $150K for 2 years from the National Science Foundation. The award, which is part of the NSF's "Energy, Power, and Adaptive Systems" program is entitled "EAGER: Modeling Network Dynamics in the Epileptic Brain to Develop Translational Tools for Seizure Localization and Detection". The study is a collaboration with the Epilepsy Center at JHMI.

From the Grant abstract:

"Epilepsy affects 60 million people worldwide who suffer from recurrent seizures, and 40% of patients do not respond to any drug therapy. These patients would greatly benefit from closed-loop neurostimulation therapy to suppress seizures, but the efficacy of such therapy critically depends on whether the stimulus is administered close to the seizure origin (epileptogenic zone, EZ) and immediately prior to or at seizure onset. This program develops novel computational tools for effective EZ localization and seizure onset detection from multi-channel intracranial EEG (iEEG) recordings."

More details can be found about the award on the NSF website here.

Congratulations Sabato!

Dr. Natalia Trayanova's Research Featured in SIAM Connect News Site

Date: July 22, 2013

Dr. Natalia Trayanova, Murray B. Sachs Professor of Biomedical Engineering and member of the Institute for Computational Medicine was featured in "SIAM Connect", The Society for Industrial and Applied Mathematics' news site. The article, The beat goes on: Modeling the human heart is under the rubric "Explaining Applied Math Research", and is based on the keynote address Dr. Trayanova delivered at the Annual AiAM meeting in Boston earlier this year. A brief video overview of her talk and an interview with Dr. Trayanova conducted after her keynote lecture can be found here.

Dr. Sridevi Sarma speaks at SIAM DS13 symposium

Date: July 17, 2013

Dr. Sridevi Sarma, presented at the 2013 SIAM (Society for Industrial and Applied Mathematics) Conference on Applied Dynamical Systems. The conference was held at the Snowbird Ski and Summer Resort, Snowbird, Utah, USA, from May 19-23. Dr. Sarma's presentation was entitled "On the Therapeutic Mechanisms of Deep Brain Stimulation for Parkinson's Disease: Annihilation or Restoration?"

From SIAM's site: "The application of dynamical systems theory to areas outside of mathematics continues to be a vibrant, exciting and fruitful endeavor. These application areas are diverse and multidisciplinary, ranging over all areas of applied science and engineering, including biology, chemistry, physics, finance, and industrial applied mathematics. This conference strives to achieve a blend of application-oriented material and the mathematics that informs and supports it. The goals of the meeting are a cross-fertilization of ideas from different application areas, and increased communication between the mathematicians who develop dynamical systems techniques and applied scientists who use them."

To view a video of the presentation, click here.

To view pdf slides, click here.

Dr. Tilak Ratnanather and Daniel Tward of the ICM to be honored with Farrington Daniels Award

Date: July 12, 2013

The American Association of Physicists in Medicine (AAPM) have selected the best paper published in Medical Physics in 2012 — “Effects of protocol and obesity on dose conversion factors in adult body CT.” This honor will be marked with receipt of the prestigious Farrington Daniels Award, which is bestowed yearly to the authors of the most outstanding paper on radiation dosimetry.

Johns Hopkins biomedical engineering authors Tilak Ratnanather, D.Phil, and graduate student Daniel Tward will be presented with the award in a ceremony on August 5, 2013, in Indianapolis, IN. Both Ratnanather and Tward are associated with the Center for Imaging Science.

In the paper the researchers concluded that obesity has a significant effect on computed tomography dose and risk conversion coefficients — which cannot be predicted using body diameter alone — and that size-specific dose estimates generally overestimate organ dose for obese patients.


Dr. Natalia Trayanova Featured in Johns Hopkins Engineering Magazine

Date: July 10, 2013

Dr. Natalia Trayanova, Murray B. Sachs Professor of Biomedical Engineering and the Institute for Computational Medicine, is featured in the summer 2013 edition of The Johns Hopkins Whiting School's Engineering Magazine. “She's Got the Beat” focuses on research in Dr. Trayanova's lab to unravel complexities in the nonlinear landscape which lead to heart disease.

As stated in the article, “From the outset, Trayanova’s lab has been focused on modeling strategies that examine the basic mechanisms of heart disease and shed light on what’s going on and why in an ailing heart. But Trayanova has always had her sights set on the step beyond that as well—delivering clinical innovations. That’s an area where her team is now making exciting progress.”

To read the entire article at the Johns Hopkins summer 2013 Engineering Magazine, click here

Dr. Natalia Trayanova gives keynote lecture at IEEE Engineering in Medicine and Biology Society

Date: July 6, 2013

Natalia A. Trayanova, Murray B. Sachs Professor of Biomedical Engineering and the Institute for Computational Medicine, presented a keynote lecture at the 35th Annual Conference of the IEEE Engineering in Medicine and Biology Society. The conference was held on July 3-7 in Osaka, Japan. Natalia's presentation entitled “Modeling Heart Function and Dysfunction” was scheduled for theme 5 in the keynote speaker series.

Click here to view more information about the conference.

To view a pdf abstract of Dr. Trayanova's presentation, click here.

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